Antibody studies in New York

United States // 06 November, 2020

6 November: Another study on antibody prevalence in New York City has been published, in Nature. More than 10,000 plasma samples collected from patients at Mount Sinai Hospital between early February and early July were analysed.

Around 20% of people were found to have antibodies to SARS-CoV-2, the virus which causes COVID-19. This equates to around 1.7 million people in New York City being infected by late May. The authors state that given the deaths reported by 19 May equaled 16,674, the overall case fatality rate is around 1%.

They also found samples which were positive in mid-February which is earlier than the first case was confirmed on 1 March.

As well as witnessing an increase in positive samples which mirrored the epidemic transmission peaking in March-April, the authors found “From May to July seroprevalence stayed stable, suggesting lasting antibody levels in the population.” Ongoing seroprevalence studies are planned to further establish whether antibodies levels are long lasting.

19 June: A large seroprevalence study was conducted among adults across New York State during the second half of April. The findings have been published in Annals of Epidemiology.

Over 15,100 blood samples collected from people at grocery stores were analysed. Of these around 14% were found to have antibodies to SARS-CoV-2, the virus responsible for COVID-19. Regional variations were found, with new York City having the highest incidence of around 22% positive. Some racial variations were noted, with over 29% of Hispanic/Latino people and over 20% of non-Hispanic black/African American people testing positive.

The authors estimate that based on these findings, over 2 million adults in New York State were likely infected with COVID-19 by the end of March.

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